American Board of Pathology (ABPath) Practice Test 2026 - Free Pathology Exam Practice Questions and Study Guide

Acinar cell adenocarcinoma, a tumor that originates from the acinar cells of the pancreas, is classified as an exocrine type tumor. This classification is based on the nature of the cells from which the tumor arises. Acinar cells are responsible for producing digestive enzymes, which are secreted into the pancreatic duct and ultimately enter the gastrointestinal tract.

Exocrine tumors are those that derive from glandular tissues that secrete their products through ducts rather than directly into the bloodstream, which is characteristic of endocrine tumors. In the case of acinar cell adenocarcinoma, the tumor exhibits features typical of exocrine secretory products, reflecting its origin and supporting its classification in this category.

In contrast, endocrine tumors are composed of cells that secrete hormones directly into the bloodstream, lymphoid tumors are related to the immune system (specifically to lymphatic tissues), and mixed tumors contain elements from both endocrine and exocrine lineages. Given the context of acinar cell adenocarcinoma, its classification as an exocrine type aligns with its biological behavior and cellular characteristics.