American Board of Pathology (ABPath) Practice Test 2025 - Free Pathology Exam Practice Questions and Study Guide

Question: 1 / 400

True or False: Autosomal Recessive Polycystic Disease results in multiple large cysts within the kidneys.

True

False

Autosomal Recessive Polycystic Kidney Disease (ARPKD) is characterized by the presence of small, dilated cystic structures in the renal collecting ducts. Unlike Autosomal Dominant Polycystic Kidney Disease (ADPKD), which leads to the formation of large cysts, ARPKD typically involves smaller cysts that are numerous and can cause significant renal dysfunction. The pathology of ARPKD is primarily associated with developmental defects in the kidney and liver, leading to renal enlargement and associated complications.

Although the disease can lead to variable severity and complications, it is important to note that the form and size of the cysts are defining characteristics of the disease type. Therefore, stating that ARPKD results in multiple large cysts is inaccurate, thus supporting the choice of "False" as the correct statement.

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True, it is always severe

False, small cysts are present

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